A team of US scientists has shown that exposure to phthalates, in early pregnancy, increases the risk of newborn boys having genital abnormalities. The researchers found that for every factor of ten increase in the sum of metabolites of di(2-ethylhexyl) phthalate (DEHP) in urine during the first trimester of pregnancy, there was a statistically significant 2.5-fold increase in having an anomaly or a three-fold increase in Hydrocele alone. Hydrocele is retention of fluid around the testis, which is common and normally resolves itself in newborn, but is a symptom of abnormal development. The researchers conclude the study “suggests that prenatal exposure to DEHP may exert adverse effects on genital development in utero, leading to higher incidence of hydrocele”. They recommend that future studies include hydrocele in their examinations. The research team, led by Sheela Sathyanarayana from Washington School of Medicine in Seattle, studied a group of 371 mothers and sons from California, New York State, Minneapolis and Seattle between 2010 and 2012. The data was available from The Infant Development and Environment Study (TIDES), which measured urinary phthalate metabolites in mothers and monitored birth outcomes. The team report in their paper, published in Environmental Research, that few cases of hypospadias and undescended testis occurred in the group, but the most common abnormality was hydrocele. The study group included:
https://chemicalwatch.com/49444/dehp-linked-to-hydrocele-genital-anomaly-in-newborns
0 Comments
|
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |